Amazon, Perplexity and OpenAI Vie to Become Healthcare’s AI Gateway

Amazon completed its $3.9 billion acquisition of primary-care provider One Medical on February 22, 2023, and integrated it with Amazon Pharmacy and AWS infrastructure. Health AI is built on a multi-agent architecture using Amazon Bedrock and can access medical records with users' consent. The move extends Amazon's e-commerce gateway into healthcare services while drawing greater attention to privacy and clinical safety.

Amazon announced on March 10, 2026, that Health AI would expand beyond One Medical members to Amazon.com and Amazon App users across the United States, with access rolling out over several weeks. Available around the clock, it can explain test results and medical records, manage prescription renewals and book appointments. Eligible Prime members can receive up to five message-based consultations at no charge, covering more than 30 common conditions and worth as much as $145.

Singapore’s national health technology agency Synapxe has partnered with Amazon Web Services to launch Synapxe AgentSea, a platform designed to broaden the use of generative artificial intelligence across the public healthcare system. The service allows hospital and clinic employees to create customised AI agents using natural-language instructions rather than code, while operating within a centrally governed environment intended to address healthcare security and oversight requirements.

Public healthcare staff have already created more than 10,000 AI agents on AgentSea, according to Synapxe. The tools are being used to summarise clinical records, review procurement activities and automate staff scheduling, among other administrative and operational tasks. The rollout marks a shift from isolated AI trials toward wider deployment across Singapore’s public hospitals and clinics, with Synapxe and AWS providing the shared infrastructure for staff-led automation.